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Âé¶¹ÊÓÆµ Comments on the Temporary Scheduling of 7-OH
On July 30, 2026, ASAM submitted comments to the US Department of Health and Human Services (HHS) regarding the proposed temporary scheduling of 7-hydroxymitragynine (7-OH), recognizing concerns about the risks associated with concentrated 7-OH products, including dependence, withdrawal, inconsistent product composition, and limited regulatory oversight. ASAM highlighted that the current scientific evidence is insufficient to support any specific concentration or quantity threshold as a validated indicator of an imminent public safety risk.
Âé¶¹ÊÓÆµ recommended that any interim thresholds be described as precautionary measures subject to reassessment as new data becomes available. ASAM also called for expanded research on 7-OH's pharmacology, toxicology, dependence and withdrawal potential, and real-world health impacts, while encouraging policymakers to explore a broader FDA regulatory framework for psychoactive botanical products that would strengthen product safety, labeling, surveillance, and consumer protections.
Read ASAM's comments